Alzheimer’s Disease: What If There Was A Cure?

Dr. Mary Newport

Mary T. Newport, M.D. grew up in Cincinnati, Ohio, attended Xavier University for pre-medicine, and graduated from the University of Cincinnati College of Medicine in 1978. She trained in Pediatrics at Children’s Hospital Medical Center in Cincinnati and completed her fellowship in neonatology, the care of sick and premature newborns,at the Medical University Hospital in Charleston, SC. She practiced neonatology in Florida since 1983 and served as founding medical director for two newborn intensive care units. After taking some time off to care for Steve, she resumed medical practice at the opposite end of the spectrum and is now making home visits to patients who are in end-of-life hospice care. Dr. Newport has been married to Steve Newport since 1972 and they have two daughters and a grandson.

 

Mary NewportIn 2008, she wrote an article, “What If There Was a Cure for Alzheimer’s Disease and No One Knew?” relaying her family’s experience with this disease and her research into a dietary intervention that may benefit persons with Alzheimer’s and other neurodegenerative diseases. September 27, 2011, marked the date of the release of her book, Alzheimer’s Disease: What If There Was A Cure? The Story of Ketone.The Second Edition was released in April 2013. The book has also been translated and published in German, Japanese and French. Her latest effort was released in August 2015, entitled The Coconut Oil and Low-Carbohydrate Solution for Alzheimer’s, Parkinson’s and Other Diseases, a practical guide to using coconut oil and MCT oil and a sensible approach to lowering carbs in the diet to increase ketones, which provide alternative fuel for the brain

Mary Newport

 

This just skims the surface of what Coconut Oil did for my husband, Steve Newport in under 2 months:

alzheimer's clock test 1
Alzheimer's clock test
alzheimer's clock test

An Update from Dr. Mary Newport

Ketones and Alzheimer's

Steve & Mary Dec. 2008 (6mths after starting coconut oil)

February 23, 2016

It has been nearly 8 years since Steve improved with coconut oil. He improved very significantly and steadily the first year and remained stable for 2 more years. He began having seizures in summer 2013 starting with a head injury from a fall and did not fully recover. In spite of this serious setback, I feel it was well worth the extra quality time that we had together as a family. He remained in our home with the help of our wonderful caregivers and had minimal further worsening over the next two years. I cannot help but think that ketones played an important role in all of this. Although he lost his battle with Alzheimer’s on January 2, 2016, at age 65, there is now at least hope for others who are at risk or in earlier stages of this horrible disease, and their families might actually win their fight. We will continue to bring more awareness and research to this and future projects to find a cure.
I want to thank everyone who has sent me testimonials for your loved ones who have tried coconut oil and or MCT oil. I have received over 400, and while some people have no response, the vast majority has reported improvements in cognitive functions and overall quality of life. I am overjoyed that so many people have benefited from this food-based intervention as my late husband Steve! These testimonials have helped to get grants for research at the University of South Florida (USF) Byrd Alzheimer Institute, where humane animal studies have been completed and a clinical trial of coconut oil in 65 people with mild to moderate Alzheimer’s disease is underway, funded by an anonymous foundation. This is a pilot study that will look at whether there is symptomatic improvement and also if this treatment will delay progression to Alzheimer’s disease. Several small and larger studies are taking place in the USA and Japan and other areas of the world, and a much larger three-year study of MCT oil for prevention of Alzheimer’s in people with mild cognitive impairment will take place in Canada, funded by the Alzheimer’s Association.

Steve asked for his brain to be donated to the Florida Brain Bank which is a research study for Alzheimer’s disease and other dementias. We hope to find what he truly suffered from, be it Alzheimer’s or Lewy Body, or a combination of these two horrible diseases, and if ketones produced a visible impact on his brain to aid in the search for a cure.

Ketones as an alternative fuel are also under study at USF in the lab under the direction of Dominic D’Agostino, Ph.D. for the treatment of cancer, ALS (Lou Gehrig’s disease), wound healing, oxygen toxicity, epilepsy, and status epilepticus, using ketogenic diets that contain medium chain triglycerides and also ketone esters.  The cancer studies are looking at combinations of ketogenic diets with hyperbaric oxygen and glucose lowering substances to further enhance the effect on killing cancer cells, which thrive on glucose but cannot use ketones while preserving normal cells. Results of several of these studies have now been published and others are forthcoming.

Studies of ketone esters for Alzheimer’s, Parkinson’s and other neurodegenerative diseases urgently need to be undertaken but funding for mass production of the ester and clinical testing has not yet materialized.  For now, you can provide ketones to the brain as an alternative fuel by consuming foods that contain medium chain triglycerides to produce ketones. What do you have to lose?

Alzheimer’s disease now affects more than 5.5 million Americans

Coconut oil helps Alzheimer's, dementia, ALS, MS shared a link. ...

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RESPONSE TO AHA ADVISORY COMMITTEE ON DIETARY FATS AND CARDIOVASCULAR DISEASE
By Mary T. Newport, M.D.
June 21, 2017 - for more information on coconut oil and ketones please see my website at www.coconutketones.com.

From Mary T. Newport, MD: The media has irresponsibly taken viral a fragment of information purporting that coconut oil may be bad for your heart from an article published in the medical journal "Circulation" 2017, 135:e1-24, as a presidential advisory committee report from the AHA, "Dietary Fats and Cardiovascular Disease". The four "core studies" this committee relied on were all conducted in the 1950s, were relatively small groups of men only in three of the four studies, were conducted in populations that almost certainly were not consuming coconut oil on any regular basis, and were studies comparing diets with ANIMAL saturated fats to diets with polyunsaturated fats. Animal and human fat is well known to store hormones, pesticides, antibiotics and other environmental substances, which could be a factor in heart disease, whereas vegetable fats such as coconut oil would not be so likely to contain these potentially harmful substances. The authors do not mention whether age and smoking were controlled for in these studies; smoking, which was very prevalent in the 1950s compared to the 2010's is a major contributor to heart disease. The raw numbers of how many people in each group had cardiac events was not presented, making the summaries difficult to evaluate. The clincher in this article is that they state on page e13, under the section on coconut oil, "Clinical trials that compared direct effects on CVD [cardiovascular disease] of coconut oil and other dietary oils have not been reported." They rely on studies of individual saturated fatty acids that show a miniscule increase in LDL (co called "bad") cholesterol but rationalize away a similar small increase in HDL ("good")and an improved LDL to HDL ratio. For example, lauric acid (50% of coconut oil) resulted in a less than 1 mg/dl point increase in both LDL and HDL cholesterol, with typical LDL values ranging from less than 100 to 160 mg/dl. Could a change of less than 1 mg/dl really have that much impact? In addition, the problem here is that natural fats such as coconut oil and even lard do not come as individual fatty acids but rather combinations of many fatty acids which may balance each other out. Completely ignored in this report are the saturated fats in coconut oil known as medium chain triglycerides that could balance out the longer chain fats. Coconut oil also contains some mono- and polyunsaturated fats. One of the important details that the AHA is missing here is that 70% of the saturated fats in coconut oil are medium chain triglycerides (C6 through C12, lauric acid) which are either converted to ketones or burned immediately as fuel by muscle and other organs and not stored as fat. Lauric acid has some properties of medium chain and longer chain fatty acids. Ketones come from breakdown of fat and provide an alternative fuel to the brain and most other organs during starvation or fasting or to cells that are insulin resistant. In a recent study conducted in Japan, lauric acid was found to potently stimulate ketone production in astrocytes in cultures; astrocytes are brain cells that nourish other brain cells. By comparison, butter, lard and animal fat contain minimal medium chain triglycerides and they are not found in soybean, olive, corn, safflower and most other oils. There are hundreds of studies of potential benefits of coconut oil; for example, lauric acid, which is a medium chain triglyceride and about 50% of coconut oil, is antimicrobial - there are numerous studies showing that lauric acid kills many bacteria, viruses, fungi like candida and protozoa. A few small cholesterol studies looking at coconut oil were conducted decades ago in animals or a few men over short term and used hydrogenated coconut oil - any hydrogenated oil will increase cholesterol. Also, the diets were deficient in omega-3 fatty acids which can also increase cholesterol levels. There are studies of entire populations for whom coconut oil provides 1/3 to 2/3 of the diet showing that they were of normal height and weight, had normal blood pressure, triglycerides and cholesterol levels at all ages. The committee surmises that people who eat saturated fats likely have other bad eating habits without any proof. These days, the people who embrace coconut oil are likely embracing healthier foods as well and a healthier lifestyle in general and eating fish and/or taking omega-3 fats, which weren’t on the radar in the 1950s when the so-called “core studies” for this report were conducted.
The folks in the AHA and other organizations who perpetuate these myths about coconut oil need to really do their homework and learn more about medium chain triglycerides and study the other beneficial effects of coconut oil, which they choose to ignore. The bottom line that came out of their lengthy report is that “coconut oil is bad for your heart”, which has now been perpetuated by media who jumped on this conclusion that is not even based on direct research of coconut oil and heart disease. This message has gone viral worldwide. The impact of this could take a devastating toll on the economies of countries that produce coconut oil, mostly made up of individual farmers and their families trying to make a living. These economies were devastated in the 1960s and have been slowly recovering from the initial similar AHA statement on saturated fats in 1961 based on the same four “core studies". It is irresponsible and unconscionable for this advisory committee to make such sweeping claims without direct proof that coconut oil causes heart disease.
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Dr. Mary Newport Talks About Ketones - Part III (internet problem!!) ...

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Dr. Mary Newport Talks About Ketones Part II of III (internet problem!!) ...

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