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New Important Article on Ketone Ester from Dr. Richard Veech NIH

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New Important Article on Ketone Ester from Dr. Richard Veech NIH

 

A groundbreaking research study of a ketone ester in an Alzheimer’s mouse model was released for publication January 4, 2012, in Neurobiology of Aging by Yoshira Kashiwaya, M.D. and others in the laboratory of Dr. Richard L. Veech at the NIH in Rockville, Maryland. This study showed that, compared to animals fed a normal control diet, the Alzheimer’s model mice who were fed the ketone ester (D-beta-hydroxybutyrate-(R)-1,3-butanediol) had significantly less amyloid and tau protein that form the plaques and tangles in the Alzheimer’s brain, and the animals showed reduced anxiety, and improved learning and memory compared to the mice fed the control diet.

The Alzheimer brain in people becomes resistant to insulin beginning at least ten to twenty years before symptoms appear and this affects the ability of the brain cells to use glucose causing them to malfunction and die. It was discovered in the late 1960’s in the laboratory of George Cahill, M.D. (now deceased) that the brain easily switches over to using ketone bodies as an alternative fuel during starvation when glucose supplies are used up. This new research is the culmination of decades of research that followed, and, for the first time, shows that ketones could lessen the changes that occur in the brain and also improve cognitive function in this disease. In addition to acting as an alternative fuel, ketones mimic some of the effects of insulin and are also anti-inflammatory. Inflammation is another key feature affecting the Alzheimer’s brain.

Toxicity studies have already been conducted of the ketone ester in people showing there are no adverse effects and it has been approved by the FDA as “Generally Regarded as Safe (GRAS)”. Funding is now urgently needed to mass produce this ketone ester and conduct human clinical trials.

A copy of the entire article may be obtained on my website at the top of the first page www.coconutketones.com.

New Interview Series – Ketones and Alzheimer’s

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New Interview Series – Ketones and Alzheimer’s

I had the opportunity to give an interview for Scott Peters of iHealth Tube Video while at a conference where I was speaking. Here are links to the various segments:

Tampa Bay Times Article – Byrd Alzheimer’s Institute to study coconut oil in people with Alzheimer’s!

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Tampa Bay Times Article – Byrd Alzheimer’s Institute to study coconut oil in people with Alzheimer’s!

Here is a link to the story:

http://www.tampabay.com/news/health/spring-hill-couple-inspires-research-into-coconut-oil-for-alzheimers/2124596

This story spawned a similar TV story on ABC Action News that aired in the Tampa Bay area.  I will post a link when I receive it.

Sorry, I have not posted here much lately!  I have been more active on Facebook.  Just look up Mary Newport and ask to be friends.

The second edition of my book was released a couple of months ago.  There is a link to order from Amazon on my website www.coconutketones.com.

TED x USF talk link

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I have been having trouble getting by drafts to publish on my blog lately but now appear to be okay!

Here is a link to a TED talk I did in February at TEDxUSF in later February – 18 minutes long:

http://www.youtube.com/watch?v=Dvh3JhsrQ0w

Dr. Stephanie Seneff of MIT

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Dr. Stephanie Seneff of MIT on Cholesterol, ApoE4, Statins, Beta Amyloid and Alzheimer’s

Here is a link to a very thorough and highly researched article by Dr. Stephanie Seneff of MIT discussing the importance of fat and cholesterol, how they work in the brain, why statin use may be counterproductive for people at risk for and dealing with Alzheimer’s, the function of beta amyloid and why a high-fat diet may be beneficial.  I found this especially enlightening in its explanation of how cholesterol is packaged as it is transported throughout the body, and what it is packaged within LDL particles, for example, may be a surprise.

http://coconutoil.com/the-clue-to-why-low-fat-diet-and-statins-may-cause-alzheimers/

Dr. Seneff has written many other similar articles of great interest to those concerned with cholesterol, statins, Alzheimer’s, autism and other neurodegenerative diseases, many of which can be downloaded from her homepage. http://people.csail.mit.edu/seneff/

The Eating Academy – Good articles on ketosis and many other topics by Dr. Peter Attia

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Here is a link to a blog by Peter Attia, MD on nutrition, stressing low carbohydrate diet with many very interesting articles on ketosis (see part I and Part II).

 

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Alzheimer’s disease now affects more than 5.5 million Americans