New Important Article on Ketone Ester from Dr. Richard Veech NIH

New Important Article on Ketone Ester from Dr. Richard Veech NIH

Mary Newport MD 5 comments

New Important Article on Ketone Ester from Dr. Richard Veech NIH


A groundbreaking research study of a ketone ester in an Alzheimer’s mouse model was released for publication January 4, 2012, in Neurobiology of Aging by Yoshira Kashiwaya, M.D. and others in the laboratory of Dr. Richard L. Veech at the NIH in Rockville, Maryland. This study showed that, compared to animals fed a normal control diet, the Alzheimer’s model mice who were fed the ketone ester (D-beta-hydroxybutyrate-(R)-1,3-butanediol) had significantly less amyloid and tau protein that form the plaques and tangles in the Alzheimer’s brain, and the animals showed reduced anxiety, and improved learning and memory compared to the mice fed the control diet.

The Alzheimer brain in people becomes resistant to insulin beginning at least ten to twenty years before symptoms appear and this affects the ability of the brain cells to use glucose causing them to malfunction and die. It was discovered in the late 1960’s in the laboratory of George Cahill, M.D. (now deceased) that the brain easily switches over to using ketone bodies as an alternative fuel during starvation when glucose supplies are used up. This new research is the culmination of decades of research that followed, and, for the first time, shows that ketones could lessen the changes that occur in the brain and also improve cognitive function in this disease. In addition to acting as an alternative fuel, ketones mimic some of the effects of insulin and are also anti-inflammatory. Inflammation is another key feature affecting the Alzheimer’s brain.

Toxicity studies have already been conducted of the ketone ester in people showing there are no adverse effects and it has been approved by the FDA as “Generally Regarded as Safe (GRAS)”. Funding is now urgently needed to mass produce this ketone ester and conduct human clinical trials.

A copy of the entire article may be obtained on my website at the top of the first page www.coconutketones.com.


Judy Bennett

December 15, 2016 at 12:51 pm

This is such important and exciting information. My mother is experiencing dementia and I have been searching
everywhere for anything to help her. This information is a blessing from God! Any suggestions would be greatly appreciated. Thank you Dr. Newport and Dr. Veech, and may God bless you for all of your work. What can “we” do to help get your information out to others and to help find the funding needed?



    January 9, 2017 at 5:56 pm

    Judy, we’ll be more than happy to assist you in supplementing your mothers diet. Please send us an email with good contact information and one of our team will reach out to you. Please send the email to: Ketones08@aol.com



December 28, 2016 at 8:37 pm

My father has Alzheimer. And I want to buy this Ketone Ester product. Could someone help me with this?



    January 3, 2017 at 3:02 pm

    We would love to help you out. Have you visited http://marynewport.pruvitnow.com ? If you need more assistance please send an email with you contact information to betterin60@gmail.com. Please include your name and phone number so we can call you.


Betty Zimbelman

February 8, 2017 at 4:23 am

Does the ketone diet seem to have a great effect on Parkinsons in comparison to alzheimers? My 84yr. old husband is having more problems with parkinsons having had it about 15 years,. He is on Sinemet and also has diabetes II. I am looking for something that might help him in some measure.
Thank you.


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Alzheimer’s disease now affects more than 5.5 million Americans

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