Alzheimer's, Parkinson's & Dementia

THE STORY OF KETONES

Dedicated to people with Alzheimer’s, Parkinson’s, dementia, and other neurological diseases, their families, and caregivers…and for people who want to prevent these tragic diseases.

Ketones are an alternative fuel to glucose for the brain. In many brain disorders, there is a problem getting glucose into brain or nerve cells.

Ketones are anti-inflammatory. Inflammation is also a key factor in these disorders.

Providing ketones through MCT and coconut oil, ketogenic diet, and/or ketone supplements could help. Many people combine all of these strategies along with overnight fasting and exercise, which also increase ketone levels.

Caregivers need more energy too!

PAGE INDEX (Keep scrolling down!)

Coconut Oil and MCT Oil

Ketone Esters

Ketone Salts

Ketogenic Diet

Helpful Organizations

Also Look at Safety and Other Helpful Dementia Care Supplies

Reference List for studies and reviews of ketones, coconut oil, MCT oil, Alzheimer’s, and mild cognitive impairment

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COCONUT OIL & MCT OIL

Increase brain energy & fight inflammation

Virgin Coconut Oil contains:

MCTs (medium-chain triglycerides) are fats that boost ketone levels into the “mild ketosis” range. Coconut oil is the richest natural source of MCTs. MCT oil is extracted from coconut oil.

Lauric acid (50% of coconut oil) has many properties of MCTs, kills many microbes (article on lauric acid) that have been implicated as triggers or accelerants of Alzheimer’s, and potently stimulates ketone production in astrocytes, which are brain cells that nourish neurons. (Studies in cultured astrocytes).

Polyphenols in coconut oil are antioxidants and reduce inflammation; some polyphenols inhibit formation of plaques or promote myelin repair.

Virgin coconut oil increases HDL cholesterol. Most studies show little or no increase of LDL with virgin coconut oil.

How to Use Coconut Oil & MCT Oil

Diet Guidelines for Coconut Oil and MCT Oil by Dr. Mary Newport

Coconut Oil & MCT Oil Mixture: MCT//143. Fixed income? Easy Recipe for MCT & Oil Mixture.

Trouble digesting MCT or coconut oil?

Pure Encapsulations Pancreatic Enzymes could help!

How could coconut oil help Alzheimer’s?

Potential of coconut oil and medium chain triglycerides in the prevention and treatment of Alzheimer’s disease. Chatterjee P, et al. Mech Aging Devel (2020); 186:e1-10. Full Article – Suppl Materials

What If There Was a Cure for Alzheimer’s and No One Knew? (English)(Spanish) (2008) by Dr. Mary Newport

Case Study in Alzheimer’s & Dementia (2015) – Steve’s remarkable response to coconut oil/MCT oil and the Veech ketone ester from the NIH.

MCT study (one of many!): Alzheimer’s and Dementia in 2020 – In study of 65 people with mild cognitive impairment for six months, 30 ml per day (2 tablespoons) MCT Oil increased brain energy as ketones and improved scores on memory tests in people with mild cognitive impairment.

Complete Reference List: Coconut Oil, MCT Oil, & Ketones – Studies and Reviews

Still Worried About Cholesterol? Leading Scientists Agree: Limits on Saturated Fats No Longer Justified (2020)

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MCT//143 from Pruvit – 1/2 oz. packets or 17-ounce bottle (33 servings)

Based on “Steve’s Oil” and formulated by Mary Newport, MD for Pruvit.

Contains MCT from coconut oil + virgin coconut oil + phosphatidylcholine which is important to brain cells and formation of acetylcholine, the “memory” neurotransmitter.

Look for other MCT and coconut oil products on the

Ketone, Coconut Oil, and MCT Oil Supplements Page

KETONE ESTER

Rapidly Increases Brain Energy with Highest Ketone Levels

The ketone ester (a combination of R-betahydroxybutyrate and R-butanediol) was invented by Richard Veech, MD, PhD at the NIH and studied intensively by Dr. Kieran Clarke at Oxford University.

The Power of Ketones: Ginny talks again

Jonny and his Gramma Ginny 3:07 minute video, filmed May 2 & 4, 2018 – Watch Here

People often ask me if it is worth trying ketone salts and ketone esters in the latest stages of Alzheimer’s and other dementias. This video suggests it could be worth a try.

Jonny Bonilla-Bowman, a nursing student, takes small amounts of the ester for his traumatic brain injury. In May of 2018, Jonny gave his 97-year-old grandma, Virginia Bowman, who was diagnosed with dementia some years earlier, a larger (28-30 ml = 14 to 15 grams betahydroxybutyrate) dose of the ester. The results of the first dose led him to film her on the second and fourth days.

How Do Ketone Esters Work?

Ketone Esters: What, Why, and How? An article by Mary T Newport MD

Videos on What Ketones Do by Mary T Newport MD

Ketone Ester is Safe for general public – 28-day study (2019)

More than 2000 doses of the R-3-hydroxybutyl/R-3-hydroxybutyrate Veech ketone ester were given over 28 days to 24 volunteers ages 19 to 70 at large doses of 25 grams three times per day. There were only 11 mild adverse events in 2,016 drinks – 6 reported nausea for one dose, 3 reported mild headache, 1 reported diarrhea, and 1 reported abdominal discomfort.

Ketone Ester Study in Progress!

Scientific article here on study protocol – Finishes 2024

Where To Find Ketone Esters

Note: Recommended doses on package are for endurance athletes – doses that might help symptoms of dementia and Alzheimer’s may be much smaller (after doctor’s approval suggest starting with 2.5 or 5 gm BHB. Many people report better sleep with just 2-3 gm BHB. Discuss with your doctor!

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NEW PRODUCT: Cognitive Switch Liquid from Juvenescence

Creamy light berry flavor – Best tasting ketone ester!! Suggest starting with 1 level tablespoon = 5 grams BHB once or twice per day, then increase as tolerated (5 tablespoons per bottle).

A ketone diester combining the medium-chain triglyceride C8 and 1,3-butanediol which both convert to the ketone betahydroxybutyrate (BHB).

Testing on myself (Dr. Newport) showed ketone levels and lowering of blood glucose sustained for several hours longer than other ketone ester products.

6 bottles cost $59.99 which equals $0.40 per gram BHB BUY NOW

Also comes as a flavorless powder!! See below!

NEW PRODUCT: Cognitive Switch Flavorless Powder

A truly flavorless ketone ester powder. Looks creamy in water, coffee, tea, or you can add to other favorite drinks.

Each packet or scoop = 12.5 grams betahydroxybutyrate (BHB). I suggest starting with 1 level tablespoon = about 4 grams BHB once or twice per day, then increase every few days as tolerated.

$59.99 for jar with 12 servings of 12.5 grams in each scoop = $0.40 per gram BHB BUY NOW

KetoneAid KE4

Ketone ester (D-betahydroxybutyrate + D-1,3-butanediol)

Veech/Clarke ester – “Scary Cherry” A little scary 🙂 but improved – Highest peak ketone level per equivalent dose of BHB products – $0.85/gm BHB with trainer bottle subscription. Autoship discount.

3 Bottle Pack – $94.46 = $1.18 per gram BHB BUY NOW

12 Bottle Pack – $385.95 = $1.07 per gram BHB BUY NOW

Kenetik Concentrate – Good value and Taste

Mixture of D-BHB and R-1,3-Butanediol (Not combined as ester) – 10 gm D-BHB per serving – 4 servings/bottle – Three citrus flavors – Great D-BHB levels – Good Value at $87.99 for six pack (24 servings x 10 gm BHB) – $0.37/gm BHB BUY HERE

Delta H Ketone Health

Veech/Clarke ester – Ketone ester (D-betahydroxybutyrate + D-1,3-butanediol) – 10 gm BHB/bottle

3 Bottle with 10 grams per bottle = $40.00 – $1.33/gm BHB – BUY HERE

KetoUp from Pruvit

Free D-BHB buffered – Carbonated ketone beverage – Many great flavors. BUY HERE

KETONE SALTS

Increase Brain Energy for Several Hours

Ketone salts combine betahydroxybutyrate (BHB) with sodium, potassium, calcium, and magnesium. Pruvit and Real Ketones are the only companies currently selling all of their ketone salts as D-BHB, but L-BHB has other actions that may be beneficial.

What Are Ketone Salts & How-To?

Ketone Salts Explained by Dr. Mary Newport

Using Ketone Salts in the Elderly and People with Medical Conditions by Dr. Mary Newport

Explore Ketone Salts

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Pruvit Ketone Salts

10-Day Challenge from Pruvit – Only$99 for 20 packets of ketone salts of various flavors. 10-pack of MitoPlex electrolytes/vitamins with first purchase. This is an exciting, economical way to try out ketone salts. 22% discount with monthly “smartship”. Stock up during 17 to 33% sales. [Join as a promoter and earn free products and commissions.]

Keto Start from Audacious Nutrition

Raspberry Lemonade – Caffeine

Tropical – No caffeine

10 gm D- & L-BHB per packet – Great Price – $0.50 per gram BHB

Learn about D versus L-BHB – BUY HERE

Real Ketones – Real Good Price!

Variety of flavors available with and without MCT oil. BUY HERE

For product questions contact us at “Ketones08@gmail.com”.

KETOGENIC DIET

Increase Brain Energy & Fight Inflammation

If the Keto Diet Can Put Type 2 Diabetes into Complete Remission, Why Not TYPE 3 DIABETES – ALZHEIMER’S? These two case reports illustrate that this is possible:

Case Report (2019): A man with diabetes and Alzheimer’s improves

68-year old active but morbidly obese man (NOT my husband!!) with type 2 diabetes and mild Alzheimer’s reverses poorly-controlled diabetes to normal, markedly improves on memory testing (from 23 to 29 of 30 points on MoCA test), improves triglycerides and all cholesterol results and loses 15 pounds with 10-week ketogenic diet! The author shared with me that his average daily ketone level was 1.0 mmol/L which is considered “mild nutritional ketosis”. Most people could achieve this by eating less than 50 grams of carbs per day and about 50% or more of daily calories as fat (6.5 tablespoons per day equivalent of fats and oils on an 1800-calorie per day diet). Coconut and MCT oil as part of this fat can help achieve and sustain this level of ketosis. Clinical trials using ketogenic diet to treat and prevent Alzheimer’s are underway in several locations.

In, 2008, my husband Steve was “pre-diabetic” before starting coconut oil and then MCT oil for early onset Alzheimer’s, as we increased over several months to 9 to 11 tablespoons per day divided into four meals/snacks with food and reduced sugars and starchy foods, effectively a ketogenic diet, he continued to improve steadily over the first year and enjoyed almost four years of better quality of life. Did this reverse both pre-type 2 diabetes and type 3 diabetes/Alzheimer’s? See Steve’s Story on the Home page.

Case Report (2019) – A lady with Alzheimer’s and metabolic syndrome improves

71-year old female ApoE4 carrier with mild Alzheimer’s and metabolic syndrome with insulin resistance treated with a ten-week ketogenic diet and had remarkable improvement in fasting blood sugar, insulin, HbA1C, cholesterol and triglyceride profile, and her MoCA test for memory improved from 21 (mild Alzheimer’s) to nearly normal score of 28 of 30 points.

Ketogenic Diet Improves Parkinson’s Symptoms More Than Low-Fat Diet

Dr. Matthew Phillips, a neurologist in New Zealand, and associates report 42% improvement in nonmotor symptoms of Parkinson’s disease with a reasonable, healthy-food ketogenic diet compared to healthy-food low-fat diet. Both diets improved motor symptoms as well. Article – Printable Ketogenic Diet for Study & Recipes

“Keto” Diet How To – Keto Diet: Start Here!

Simple One Sheet Keto Diet Printable PDF

More Ideas for Keto Diet and Recipes Printable PDF

Help with Keto Diet for Epilepsy, Cancer, and Other Disorders – The Charlie Foundation

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ORGANIZATIONS

Alzheimer’s Association: Website – Facts and Figures Full Report 2019 — Statistics Sheet

Michael J. Fox Foundation for Parkinson’s Research – Diet: A Practical Guide

National Institutes of Health: “What Is Dementia?” Links to types of dementia

Alzheimer’s Disease International: Reports and Information on Alzheimer’s and Dementia.

Dementia Alliance International: By people with dementia for people with dementia.

Dementia Action Alliance – Dementia Discussions every Thursday at 1:00 ET, 12:00 CT, 11:00 MT, 10:00 PT. The Discussion will last one hour. Learn tips from others and share your thoughts as we discuss ways to make life easier for people living with dementia and/or care partners. Link for video chat – https://zoom.us/j/4567882023

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